{"data":{"labs":[{"nid":"9630307","body":"TBD","title":"E. coli Ribosome 23S rRNA, Round 1","created":"Dec 01, 2019","founder_uid":"57675","founder":"Omei","synthesis_winner":"386950","num_synth":"20","affiliation":null,"selection":null,"cover_image":null,"num_synthesized":20,"winners":[]},{"nid":"3293294","body":"The Reproducibilty Test Lab is a series of cloud labs that will be synthesized with each synthesis round. The idea is to run a controlled set of RNA designs over multiple synthesis rounds and compare the SHAPE results between identical designs over time.\r\n\r\nThe objectives for this series are:\r\n\r\n * Provide a consistent measure of the reproducibility of the cloud lab synthesis results, for long term quality control,\r\n * Determine how much of the variation in synthesis results is captured by the error estimates reported for each synthesized base,\r\nThe Reproducibilty Test Lab is a series of cloud labs that will be synthesized with each synthesis round. The idea is to run a controlled set of RNA designs over multiple synthesis rounds and compare the SHAPE results between identical designs over time.
The objectives for this series are:
* Provide a consistent measure of the reproducibility of the cloud lab synthesis results, for long term quality control,
* Determine how much of the variation in synthesis results is captured by the error estimates reported for each synthesized base,
* Provide some guidance as to where the synthesis process might be improved, in order to increase reproducibility, and
* Give those analyzing the synthesis data a better understanding of the variation to expect when comparing data from different synthesis rounds.\r\n\r\n*** 9/26/13 *** This got into the Active labs tab by mistake. I can't fix this myself; a developer will have to do that. But if you do have a sequence you want to suggest for the Reproducibility Lab, contact me (through the forum thread, the wiki page, or PM) directly. -- Omei","title":"Reproducibility Lab 1","created":"Sep 03, 2013","founder_uid":"57675","founder":"Omei","synthesis_winner":"12441","num_synth":"40","affiliation":"Eterna players","selection":null,"cover_image":"/sites/default/files/cloud_lab_pictures/picture-1378244610.png","num_synthesized":0,"winners":[]},{"nid":"3282859","body":"This is part of the codon riboswitch project -- another sequence that should switch when it binds histidine. [I originally posted the incorrect sequences -- thanks to brourd for catching this mistake.]","title":"Codon riboswitch [histidine]","created":"Aug 31, 2013","founder_uid":"20","founder":"rhiju","synthesis_winner":"2389702","num_synth":"63","affiliation":"Rhiju Das, Stanford University","selection":null,"cover_image":"/sites/default/files/cloud_lab_pictures/picture-1377980114.jpg","num_synthesized":0,"winners":[]},{"nid":"3281145","body":"generate the golden standard data for CE auto assign.","title":"EteRNA R43 the Backwards C","created":"Aug 31, 2013","founder_uid":"25782","founder":"Hanjoo Kim","synthesis_winner":"2389702","num_synth":"10","affiliation":"Hanjoo Kim (ACL, SNU)","selection":null,"cover_image":"/sites/default/files/cloud_lab_pictures/picture-1377924921.png","num_synthesized":0,"winners":[]},{"nid":"3281090","body":"generate golden standard for CE auto assigning data.\r\n","title":"EteRNA R45-46 FMN Aptamer with Single Binding Site","created":"Aug 31, 2013","founder_uid":"25782","founder":"Hanjoo Kim","synthesis_winner":"2389702","num_synth":"28","affiliation":"Hanjoo Kim (ACL, SNU)","selection":null,"cover_image":"/sites/default/files/cloud_lab_pictures/picture-1377924439.png","num_synthesized":0,"winners":[]},{"nid":"3280580","body":"A version of the tristable RNA that will be more robust to barcode hairpin interferences. This mutate-and-map will push forward our understanding of multi-stable RNAs.","title":"M-stable","created":"Aug 31, 2013","founder_uid":"168","founder":"tsuname","synthesis_winner":"2389702","num_synth":"41","affiliation":"Pablo Cordero, Stanford University","selection":null,"cover_image":null,"num_synthesized":0,"winners":[]},{"nid":"3280522","body":"An RNA with multiple structures predicted to be in almost equivalent portions in the ensemble. This mutate-and-map experiment will provide further insights in multi-stable RNAs.","title":"Un-stable","created":"Aug 31, 2013","founder_uid":"168","founder":"tsuname","synthesis_winner":"2389702","num_synth":"46","affiliation":"Pablo Cordero, Stanford University","selection":null,"cover_image":null,"num_synthesized":0,"winners":[]},{"nid":"3280395","body":"Correcting barcode interference issues from the last MedLoop mutate-and-map run.","title":"MedLoop resurrected","created":"Aug 31, 2013","founder_uid":"168","founder":"tsuname","synthesis_winner":"2389702","num_synth":"61","affiliation":"Pablo Cordero, Stanford University","selection":null,"cover_image":null,"num_synthesized":0,"winners":[]},{"nid":"3280109","body":"The mutate-and-map of the class I ligase, the first of several types of synthetic ribozymes produced by in vitro evolution and selection techniques and an important predecessor to the RNA replicase. What design principles can we extract from the ensemble of this molecule?","title":"Class I ligase","created":"Aug 31, 2013","founder_uid":"168","founder":"tsuname","synthesis_winner":"2389702","num_synth":"91","affiliation":"Pablo Cordero, Stanford University","selection":null,"cover_image":null,"num_synthesized":0,"winners":[]},{"nid":"3279019","body":"This is part of the codon riboswitch project -- another sequence that should switch when it binds arginine.","title":"Codon riboswitch [arginine]","created":"Aug 30, 2013","founder_uid":"20","founder":"rhiju","synthesis_winner":"2389702","num_synth":"59","affiliation":"Rhiju Das, Stanford University","selection":null,"cover_image":"/sites/default/files/cloud_lab_pictures/picture-1377885363.jpg","num_synthesized":0,"winners":[]}],"num_labs":"372"}}